• Nathaniel Morris

3 Tips for cannabis & peyote mesearch

Updated: Jan 30

Here are three important things to keep in mind on your mesearch journey.





#1 Ignore the Indica/Sativa cannabis labels

There is a common misconception that Sativa is uplifting and Indica is sedative. Every effort to look at this scientifically has debunked it entirely. Genetic testing has shown much of what we had believed about cannabis is wrong. Nearly all modern cannabis cultivars are hybrids.

Different cannabis plants do affect people differently, but these differences are not related to this Indica / Sativa distinction. With biometric sensors like heart rate monitors, you can reliably see how cannabis is affecting you, so you can go ahead and ignore the Indica Sativa label on the package.


Peyote Lab blog post about the importance of rhythm in cannabis and peyote mesearch
The Centrality of Rhythm.

#2 Only use lab-tested and ethically sourced cannabis and peyote

Much like cannabis, peyote can have very different chemical constituents, depending on what variety you purchase. This is wonderful, as it allows you to test a variety of options and discover what you respond best to. There are also several types of "false peyote". These plants are closely related to peyote, nearly identical, but do not have any of the medicinal properties. Lastly, many peyote growers treat the plants as ornamentals rather than edibles, meaning they use pesticides and fungicides that are not safe for human consumption. For all of these reasons, it is important to use lab-tested peyote. It is important that peyote be ethically sourced because it's at risk of becoming an endangered species in the wild and under threat of poaching.


#3 Control for placebo

When at all possible, have a friend help you with your mesearch experiments. A friend is nice to have for a number of obvious reasons, but for mesearch, it's important because it allows you to control for a placebo. Particularly for non-intoxicating CBD or microdose peyote experiments, testing for a placebo can often be eye-opening. If you and a friend decide to both conduct mesearch experiments, you can coordinate the administration of the medicines and agree that some of the doses will be a placebo. Every week or two, the two of you can review your notes and disclose to the other what days were placebo. Adding a "sugar pill" that could convincingly pass as the real thing is challenging to say the least. It is impossible to mistake the taste of whole-cactus, but peyote concentrates like gummies can be swallowed without much taste. When making peyote gummies, make a batch with no peyote, and add some fruit juice to both batches so some of the flavors do overlap. For CBD mesearch experiments, gelcaps are by far the easiest to create a sugar pill placebo for. To learn more about placebo-controlled experiments, check out: What is a microdose?


If you have questions about cannabis and peyote, check out the FAQ and use the search tool to find the answers you are looking for. This blog is part of a series for people who are considering trying mesearch, Mesearch 101. If you are interested in purchasing peyote or participating in future research, visit www.PeyoteAcution.com for more information.


I want to again remind everyone that I am not a doctor, and this is not intended to be medical advice. For those of you who are going to be using peyote and cannabis anyway, I hope that you are inspired to take a more scientific approach. Always talk to your health care professional before attempting any mesearch experiments.


#Peyote #PeyoteLab #Mesearch #Microdose #Psychedelics #PeyoteAuction

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